I don't know the area but could it be St Georges Place?
Fire at St. George's-in-the-East 1846 .....
"Shortly before three o'clock on Sunday morning, a fire occurred at the extensive sugar-refining house belonging to Messrs. Grant and Baldwin, 17½, St. George's Place, Back Road, St. George's-in-the-East, the whole of which, together with the valuable stock, in all upwards of £20,000, was entirely consumed. A fire taking place in the night time is always sufficiently alarming, but the consternation created in this instance may be readily imagined from the circumstance of a large building, about eighty feet in height, one hundred feet in length, and forty in breadth, being, within an hour after the above time, one mass of flame, towering several feet above the summit, and threatening destruction to St. George's Church, and the surrounding houses. Though the sugar factory is bounded by the Back Road on the north, Cannon Street [Road] on the west, Ratcliff Highway and St. George's Church on the south and east, yet it stood so far isolated from all as to keep them from injury. There was but little wind, and that being south-westerly, the parochial church was preserved.
The engines were promptly on the spot, and there being an abundance of water, immense streams were continually thrown upon the burning pile: but the flames had got too firm a hold; the contents were of too inflammable a nature to admit of the slightest check, and the flames rushed rapidly from the basement, where the fire commenced, to the seven successive storeys, until the whole mass was completely encircled in one sheet of fire; and about half-past four o'clock the roof fell in with an awful crash, partially smothering the fire, but only for a moment, as it again burst forth with redoubled fury. Subsequently a great part of the east front fell, and the south wall, with the lofty chimney, was expected to fall.
The immense stores are still partially standing, and that to the eastward, where the fire is supposed to have commenced, it is expected, contains a portion of the stock unconsumed; it is also anticipated that a portion in the lower floor may yet be recovered. The fire was not entirely subdued till nine o'clock in the morning, but throughout the day the engines were incessantly playing on the smoking ruins. The building is fully insured."
The Illustrated London News. Feb 28 1846, p.148.